Chromogenic and fluorogenic sensing of biological thiols in aqueous solutions using BODIPY-based reagents.
نویسندگان
چکیده
Judicious design of BODIPY dyes carrying nitroethenyl substituents in conjugation with the BODIPY core yields dyes that respond to biological thiols by both absorbance and emission changes. Incorporation of solubilizing ethyleneglycol units ensures water solubility. The result is bright signaling of biologically relevant thiols in the longer wavelength region of the visible spectrum and in aqueous solutions.
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عنوان ژورنال:
- Organic letters
دوره 15 1 شماره
صفحات -
تاریخ انتشار 2013